Platform mRNA manufacturing processes enables rapid clinical development
Standardized clinical material production workflow:
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Step 1 :
Pre-defined supply chain for raw materials used in processing
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Step 2 :
Platform process for plasmid production: in vitro transcription (IVT) template generation
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Step 3 :
Optimized IVT reaction for high-yield mRNA production
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Step 4 :
mRNA purification process providing consistent, high quality Drug Substance supply
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Step 5 :
Drug Product formulation based on proprietary lipids mediating efficient lipid nanoparticle (LNP) delivery
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Step 6 :
Sterile filtration and fill-finish
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Step 7 :
Standardized mRNA and LNP analytics
